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Myopia Research Today is a free monthly online journal that collates and summarizes the latest research about Myopia, including details on treatment, prevention, causes, correction.


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Laser in situ keratomileusis in a patient with presumed central cloudy corneal dystrophy of Francois.

Zaidi A, McLeod SD

Department of Ophthalmology and the Francis I. Proctor Foundation at the University of California San Francisco, California 94143, USA.

PURPOSE: To report a case of laser in situ keratomileusis (LASIK) surgery performed in a patient with likely central cloudy corneal dystrophy of Francois (CCDF). DESIGN: Observational case report. METHODS: A 48-year-old woman with likely CCDF had myopic LASIK to establish monovision. Outcome measures included visual acuity, manifest refraction, and slit-lamp examination. RESULTS: At 5-year follow-up, the patient had uncorrected visual acuity of 20/100, J1, in the right eye (OD) and 20/20 in the left eye (OS), consistent with monovision correction. Manifest refraction was -1.50 OD and -0.25 OS postoperatively; after retreatment at 1 year for regression, the left eye remained stable over the subsequent 4-year period. Slit-lamp examination revealed no progression of corneal opacities in either eye. CONCLUSIONS: LASIK may be safe and effective in patients with CCDF. Further observations of a greater number of patients are required to confirm these findings.

Published 28 February 2005 in Am J Ophthalmol, 139(2): 376-7.
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