Myopia Research Today is a free monthly online journal that collates and summarizes the latest research about Myopia, including details on treatment, prevention, causes, correction.

Multiple components of epiretinal tissues detected by triamcinolone and indocyanine green in macular hole and retinal detachment as a result of high myopia.

Sakaguchi H, Ikuno Y, Choi JS, Ohji M, Tano T

Osaka University Medical School, Department of Ophthalmology, Osaka, Japan. sakaguh@ophthal.med.osaka-u.ac.jp

PURPOSE: To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachment (MHRD) as a result of high myopia. DESIGN: Histologic study. METHODS: We excised three layers of membranes visualized with TA and ICG that were tightly adhering to the retinal surface during vitrectomy and examined them by transmission electron microscopy. RESULTS: The first membrane was made of acellular collagen fibers, suggestive of vitreous, and the second was comprised of parts of fibroblast-like cells and collagen fibrils, suggesting a proliferative epiretinal membrane. The third membrane was an internal limiting membrane. CONCLUSIONS: Multiple components of epiretinal tissue could be delaminated with the assistance of TA and ICG during surgery for myopic MHRD.

Published 4 January 2005 in Am J Ophthalmol, 138(6): 1079-81.
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