Myopia Research Today is a free monthly online journal that collates and summarizes the latest research about Myopia, including details on treatment, prevention, causes, correction. | ||||||
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Five-year outcome of LASIK for myopia.Kato N, Toda I, Hori-Komai Y, Sakai C, Tsubota K Minamiaoyama Eye Clinic, Tokyo, Japan.; Department of Ophthalmology, School of Medicine, Keio University, Tokyo, Japan. naokato@sc.itc.keio.ac.jp PURPOSE: To investigate the efficacy and safety of LASIK over a 5-year postoperative period. DESIGN: Observational case series. PARTICIPANTS: We examined 779 eyes in 402 patients with myopia or myopic astigmatism who underwent LASIK to correct their refractive errors and received regular postoperative assessments for 5 years. METHODS: Postoperative examinations were performed 1 day; 1 week; 1, 3, and 6 months; and 1, 2, 3, 4, and 5 years after LASIK surgery. MAIN OUTCOME MEASURES: We evaluated changes in uncorrected visual acuity (UCVA) (logarithm of the minimum angle of resolution [logMAR]), manifest refraction, best-corrected visual acuity (BCVA) (logMAR), intraocular pressure, corneal thickness, corneal endothelial cell counts, and complications. RESULTS: Preoperative UCVA of 1.27 improved to -0.03 at 1 day after surgery and -0.08 at 1 month and revealed minimal but significant decreases thereafter. Postoperative manifest refraction was also improved by surgery, showing minimal but significant regression after 1 year. Final BCVA loss was seen in 10 eyes of 7 patients; in 7 cases, there were obvious reasons such as the progression of cataracts in 3 eyes, epithelial disintegrity due to dry eye in 2 eyes, irregular astigmatism due to flap striae in 1 eye, and age-related macular dystrophy in 1 eye. Intraocular pressure and corneal thickness decreased by 4.0 mmHg and 76.9 microm, respectively, due to surgery, but remained stable throughout the follow-up period. Corneal endothelial cell counts (2689.0+/-232.9 cells/mm(2) before surgery) showed a statistically significant decrease at 5 years after surgery (2658.0+/-183.1 cells/mm(2); 1.2% loss for 5 years), likely within the range due to physiological age-related loss. No serious, vision-threatening, irreversible complication such as keratectasia or progressive endothelial cell loss was observed. CONCLUSION: LASIK surgery is an effective and safe procedure for correcting myopia/myopic astigmatism as long as inclusion and exclusion criteria are strictly respected. However, minimal regression occurred during the 5-year investigative period. Published 2 May 2008 in Ophthalmology, 115(5): 839-844.e2. Articles on Myopia published 4 April 2008: Detection of paravascular lamellar holes and other paravascular abnormalities by optical coherence tomography in eyes with high myopia. Ophthalmology, 115(4): 708-17. OBJECTIVE: To investigate the morphologic alterations at or around the blood vessels of the retinal vascular arcade by optical coherence tomography (OCT) in highly myopic eyes. DESIGN: Observational case series. PARTICIPANTS: Two hundred eighty-seven eyes of 149 patients with high myopia (refractive error >/=-8.00 diopters [D] or axial length >26.5 mm) were studied. Fifty-six emmetropic (+1.00 to -1.00 D) eyes and 44 eyes with low (<-6.00 D) myopia were examined as controls. METHODS: ... [Abstract] [Full-text] Season of birth, natural light, and myopia. Ophthalmology, 115(4): 686-92. PURPOSE: To investigate the possible roles of season of birth and perinatal duration of daylight hours (photoperiod) in the development of myopia. DESIGN: Retrospective, population-based, epidemiological study. PARTICIPANTS: A total of 276 911 adolescents (157 663 male, 119 248 female) 16 to 22 years old. All were Israeli-born conscripts to the Israeli Defense Forces who were examined during the 5-year period 2000 through 2004. METHODS: Noncycloplegic refraction was determined by ... [Abstract] [Full-text] Long-term follow-up of endothelial cell change after Artisan phakic intraocular lens implantation. Ophthalmology, 115(4): 608-613.e1. OBJECTIVE: To report endothelial cell densities (ECDs) and their correlation to anterior chamber depth (ACD) after implantation of the Artisan intraocular phakic lens. DESIGN: Prospective observational case series. PARTICIPANTS: Three hundred eighteen eyes of 173 myopic patients treated with the Artisan iris-fixated phakic intraocular lens (IOL). METHODS: Eyes with an ACD ranging between 2.89 and 4.5 mm were implanted with the Artisan phakic IOL. Endothelial cell density measurements were ... [Abstract] [Full-text] Articles on Myopia published 25 March 2008: Efficacy of neural vision therapy to enhance contrast sensitivity function and visual acuity in low myopia. J Cataract Refract Surg, 34(4): 570-7. PURPOSE: To evaluate the efficacy and safety of neural vision enhancement technology (NVC, NeuroVision, Inc.) to improve visual acuity and contrast sensitivity function in eyes with low myopia. SETTING: Singapore Eye Research Institute, Singapore, Singapore. METHODS: This noncomparative interventional case series comprised 20 Asian adults between 19 and 53 years of age with low myopia (cycloplegic spherical equivalence [SE] from -0.5 diopter [D] to -1.5 D in the worst eye; astigmatism not ... [Abstract] [Full-text] Importance of grating orientation when monitoring contrast sensitivity before and after refractive surgery. J Cataract Refract Surg, 34(4): 551-6. PURPOSE: To measure losses in contrast sensitivity at different orientations of grating stimuli in refractive surgery patients and show the importance of orientation when higher-order aberrations (HOAs) are altered. SETTING: Manchester Centre for Vision, Manchester Royal Eye Hospital, Manchester, United Kingdom. METHODS: Contrast sensitivity for sine-wave gratings of 12 cycles per degree was measured in 12 patients before and after different types of refractive surgery. Measurements were taken ... [Abstract] [Full-text] Control-matched analysis of laser in situ keratomileusis outcomes in high myopia. J Cataract Refract Surg, 34(4): 544-50. PURPOSE: To evaluate the outcomes of laser in situ keratomileusis (LASIK) for high myopia. SETTING: Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA. METHODS: The refractive and visual outcomes in 320 eyes (227 patients) that had LASIK for high myopia (spherical equivalent [SE] -6.00 to -10.00 diopters [D]) were analyzed. Two hundred fifty-eight eyes that had LASIK for low myopia were reviewed, and a subsequent control-matched comparative analysis of visual outcomes in highly ... [Abstract] [Full-text] Articles on Myopia published 5 March 2008: Three-year results of Artisan/Verisyse phakic intraocular lens implantation. Results of the United States Food And Drug Administration clinical trial. Ophthalmology, 115(3): 464-472.e1. OBJECTIVE: To assess the safety and efficacy of the Artisan/Verisyse phakic intraocular lens (IOL) for the correction of high myopia. DESIGN: Prospective, open-label, noncomparative, multicenter clinical trial. PARTICIPANTS: A total of 684 adults with axial myopia from -4.5 diopters (D) to -22 D were enrolled: 662 in the primary analysis group and 22 under compassionate use protocol expansion. Efficacy data are based on the 662 first eyes implanted. INTERVENTION: Implantation of the ... [Abstract] [Full-text] Articles on Myopia published 27 February 2008: Visual outcomes and associated risk factors of cataract surgeries in highly myopic Taiwanese. Ophthalmologica, 222(2): 130-5. AIMS: The purposes of this study were to describe the visual outcome of highly myopic eyes undergoing cataract surgery, to investigate associated risk factors for poor postoperative vision, and to assess postoperative complication frequency among the prevalent myopic Taiwanese population. METHODS: We conducted a retrospective, noncomparative case series study at the Department of Ophthalmology, Zhongxing Branch, Taipei City Hospital, Taiwan. High myopia was defined as axial length of 26.0 mm. ... [Abstract] [Full-text] © 2004-2008 Myopia Research Today. All Rights Reserved. |
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